Skip to main content

Frog brain development inhibited by low dose pesticide

New research published in Environmental Toxicology & Chemistry reveals that low doses of a commonly used pesticide potentially harm the Northern Leopard frog by inhibiting their brain development.

Case against chlorpyrifos stacks up

The pesticide,  chlorpyrifos, which has been used since 1965 in both agricultural and non-agricultural areas, had clear effects on Northern Leopard tadpoles’ neurodevelopment, even in situations where the pesticide did not cause a decline in the amphibians’ food source.

Diagram by Sara McClelland.

Developmental exposure to chlorpyrifos

The leopard frog (Lithobates pipiens) tadpoles were reared through metamorphosis in artificial ponds containing either 0 or 1 µg/L chlorpyrifos and either chlorpyrifos‐resistant or chlorpyrifos‐sensitive Daphnia pulexzooplankton. 

Developmental exposure to chlorpyrifos resulted in metamorphs with a relatively wider optic tectum, medulla, and diencephalon compared with controls, and this result was found regardless of the zooplankton population of the pond.

Organophosphorous pesticides contaminate surface waters throughout the USA. exposing both animals and humans to these chemicals, often at very low levels.

Lead author Sara McClelland of Duquesne University, in Pittsburgh tells us

this study demonstrates that exposure to these contaminants, even at these low concentrations, impacts vertebrate neurodevelopment.




Subscribe to The Thin End

Comments

Popular posts from this blog

Palm Oil production killing the planet

Bad trade and bad products are killing our planet. We have said this before on The Thin End. There is no better example than that of palm oil. It is used ubiquitously in so many products, and its production is a major factor destroying rainforests and threatening precious species.

Demand for palm oil is 'skyrocketing worldwide'. It is used in packaging and in so much of our snack foods, cookies, crackers, chocolate products, instant noodles, cereals, and doughnuts, and the list goes on.
Bad for the planet So, why is this so bad for the planet?

The oil is extracted from the fruit of the oil palms native to Africa. It is now grown primarily in Indonesia and Malaysia, but is also expanding across Central and West Africa and Latin America.

Palm oil production is now one of the world's leading causes of rainforest destruction, and this is impacting adversely some of the world's most culturally and biologically diverse ecosystems. Irreplaceable wildlife species like t…

Nicotine exposure in pregnancy linked to cot death

Nicotine exposure during pregnancy, whether from smoking cigarettes, or nicotine patches and e-cigarettes, increases risk of sudden infant death syndrome – sometimes known as “cot death” – according to new research published in The Journal of Physiology.

Sudden infant death syndrome (SIDS) is the sudden and unexpected death of an infant under 12 months of age occuring typically while sleeping. Failure of auto resuscitation, the ability to recover normal heart rate and breathing following gasping caused by lack of oxygen in the brain, has been recorded in human SIDS cases.



Smoking increases risk for SIDS Over the last decade, use of cigarettes has declined significantly, however, over 10% of pregnant women still smoke during pregnancy. Over recent years nicotine replacement therapies, such as nicotine patches or e-cigarettes, have been prescribed to women who wish to quit smoking during their pregnancy. However, nicotine replacement therapies may not protect infants from SIDS. 
With inc…

Maternal depression can impact child mental and physical health

Maternal depression has been repeatedly linked with negative childhood outcomes, including increased psychopathology.  Now, a new study shows that depression in mothers may impact on their children's stress levels,  as well as their physical and mental well-being throughout life.

In the study, published in the journal  Depression & Anxiety,  the researchers followed 125 children from birth to 10 years.

At 10 years old, the mothers’ and children’s cortisol (CT) and secretory immunoglobulin (s-IgA)—markers of stress and the immune system (see below)—were measured, and mother-child interaction were observed.
Psychiatric assessment  The mothers and children also had psychiatric diagnoses, and the children's externalising and internalising symptoms were reported.



Internalising disorders include depression, withdrawal, anxiety, and loneliness. They are often how we 'feel inside', such as  anger, pain, fear or hurt, but may not show it.  In contrast, externalising symptom…